Background:

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene

Applications:

ELISA, WB, IHC

Name of antibody:

GABRA1

Immunogen:

Synthetic peptide of human GABRA1

Full name:

gamma-aminobutyric acid (GABA) A receptor, alpha 1

Synonyms：

EJM; ECA4; EJM5

SwissProt:

P14867

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and Human gastric cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

52 kDa

WB Positive control:

LoVo cells

WB Recommended dilution:

500-2000