2564-83-2/TEMPO氧化反應

TEMPO，即2,2,6,6-四甲基哌啶N-氧化物，是一個穩定的硝酰自由基，可作為催化劑用于氧化反應。

反應機理

反應實例

參考文獻

1. Garapon, J.; Sillion, B.;Bonnier, J. M.Tetrahedron Lett.1970,11,4905–4908.

2. de Nooy, A. E.; Besemer, A.C.; van Bekkum, H.Synthesis1996,1153–1174. (Review).

3. Rychnovsky, S. D.;Vaidyanathan, R.J. Org. Chem.1999,64, 310–312.

4. Fabbrini, M.; Galli, C.;Gentili, P.; Macchitella, D.Tetrahedron Lett.2001,42,7551–7553.

5. De Luca, L.; Giacomelli, G.;Masala, S.; Porcheddu, A.J. Org. Chem.2003,45, 4999–5001.

6. Ciriminna, R.; Pagliaro, M.TetrahedronLett.2004,45, 6381–6383.

7. Tashino, Y.; Togo, H.Synlett2004,2010–2012.

8. Breton, T.; Liaigre, D.;Belgsir, E. M.Tetrahedron Lett.2005,46, 2487–2490.

9. Chauvin, A.-L.; Nepogodiev,S. A.; Field, R. A.J. Org. Chem.2005,47, 960–966.

10. Gancitano, P.; Ciriminna,R.; Testa, M. L.; Fidalgo, A.; Ilharco, L. M.; Pagliaro, M.Org. Biomol. Chem.2005,3,2389–2392.

11.Zhang, M.; Chen, C.; Ma, W.; Zhao, J.Angew. Chem. Int. Ed.2008,47,9730–9733.

12.Perusquía-Hernández, C.; Lara-Issasi, G. R.;Frontana-Uribe, B. A.; Cuevas-Ya?ez, E.Tetrahedron Lett.2013,54,3302–3305.

13.Zhu, X.; Wang, Y.-F.; Ren, W.; Zhang,F.-L.; Chiba, S.Org. Lett.2013,15,3214–3217.